Genetic Modification of T Cells

Our CAR-T therapies begin with collecting T cells from the patient’s immune system. These cells are then genetically modified to express special antigen receptors (CAR), enabling them to precisely recognize and destroy cancer cells.

Genetic Engineering

During genetic engineering, T cells are equipped with antigen receptors designed to recognize specific antigens on cancer cell surfaces. Our anti-BCMA and anti-CEACAM CAR-T products use advanced genetic engineering technologies to ensure the highest therapy effectiveness.

Expansion and Infusion of T Cells

After genetic modification, T cells are expanded in the lab to the necessary number, then reintroduced into the patient’s body. These modified T cells recognize and destroy cancer cells, resulting in effective therapy.

CAR-T Therapies for Solid Tumors

4Cell Therapies focuses on CAR-T treatments for solid tumors, especially pancreatic, gastric, and colorectal cancers, using CEACAM6-CAR-T technology. Solid tumors constitute 96% of all malignancies. With effective solutions demonstrated in animal models of human pancreatic cancer, 4Cell Therapies S.A. is positioned to become a global leader in this field.

CAR-T Therapies for Hematologic Cancers

Our advanced CAR-T research also includes blood cancers, particularly multiple myeloma using BCMA-CAR-T. Hematologic cancers make up 4% of malignancies. Early results show high efficacy in lab and animal models, as modified T cells target specific antigens on cancer cells, effectively destroying them. 4Cell Therapies S.A. leads in CAR-T cell therapies, offering groundbreaking cancer treatment solutions. Our advanced technology is based on key elements that ensure high efficacy and safety.

Projects

Multi-Station Cell Expansion Device

In 2023, we obtained a patent for a multi-station device for cell expansion, especially for CAR-T cells. This innovative device enables efficient and scalable CAR-T cell production, significantly increasing therapy accessibility for patients.

GMP-Compliant Production Method

We developed a GMP-compliant manufacturing method that ensures the highest quality and safety of produced therapies. Our production processes adhere to the strictest pharmaceutical standards, guaranteeing the effectiveness and reliability of our products.